Serum Protein Electrophoresis (Qualitative)
This test measures the different types of proteins in your blood using a technique called electrophoresis. It helps identify abnormalities in protein distribution that may indicate conditions like multiple myeloma, liver disease, or other disorders.
["This test helps doctors check for unusual protein patterns that could signal serious health concerns."]
Key facts at a glance
- LOINC
- 4583-1
- Short code
- Hgb G-Georg Bld Ql Elph Acid
- Synonyms
- Hgb G-Georg Bld Ql Elph Acid
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis-ph
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Electrophoresis separates blood proteins into fractions based on their size and electrical charge. Common protein bands include albumin, alpha-globulins, beta-globulins, and gamma-globulins. Abnormal patterns may appear as extra bands, missing bands, or shifts in normal distribution.
Why Might You Need This Test?
Doctors may order this test to investigate symptoms like unexplained weight loss, fatigue, swelling, or signs of organ dysfunction. It’s also used in diagnosing conditions like multiple myeloma, amyloidosis, or chronic liver disease.
Sample Collection and Preparation
A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum (the liquid part after clotting). The serum is analyzed in a lab to separate proteins by size and charge.
What to Expect Before the Test
No special preparation is needed, but inform your doctor about any medications or conditions that could affect results. Avoid alcohol or strenuous activity 24 hours before the test if instructed.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal protein patterns can indicate underlying health issues. For example, high levels of abnormal proteins may suggest multiple myeloma or other plasma cell disorders. Low albumin levels could point to liver disease or malnutrition, while unusual globulin patterns may hint at autoimmune conditions or infections.
Short name
Protein Electrophoresis
Frequently asked questions
What are the normal results?
How long does it take to get results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy