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Serum Protein Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood using electrophoresis, a method that separates proteins based on size and charge.

Quick summary

["Helps identify abnormal protein patterns that may signal conditions like multiple myeloma, liver disease, or other disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
4584-9
Short code
Hgb G-Georg Bld Ql Elph Alk
Synonyms
Hgb G-Georg Bld Ql Elph Alk
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
3.5
Ref high
5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis-ph
CPT
84132
SNOMED
110742001
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Proteins Are Being Tested?

Electrophoresis separates blood proteins into several bands, each representing distinct protein groups. These include albumin, alpha-globulins, beta-globulins, and gamma-globulins. Abnormal bands or patterns may indicate underlying health issues.

How the Test Works

A small amount of your serum is placed on a gel and subjected to an electric current. Proteins move toward the opposite charge, creating distinct bands that are later analyzed to identify their composition and quantity.

Common Uses and Why It Matters

This test is often used to diagnose conditions such as multiple myeloma (a cancer of plasma cells), liver or kidney disease, and certain autoimmune disorders. It helps doctors monitor treatment progress or detect early signs of disease.

Sample Collection and Preparation

A blood sample is drawn from your arm, and the serum is separated from blood cells. The serum is then prepared for electrophoresis in a lab setting.

Reference range

Adult: 3.5-5.0 mmol/LN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Serum protein electrophoresis plays a critical role in identifying and managing conditions that affect protein balance in the blood. Abnormal patterns can reveal hidden issues like protein abnormalities, infections, or malignancies that may not be detected by other tests alone.

Short name

Protein Electrophoresis (Serum)

Frequently asked questions

What does a protein electrophoresis test show?
It shows the distribution of different proteins in your blood, such as albumin, globulins, and other fractions. Any unusual patterns or bands may indicate conditions like multiple myeloma, liver disease, or other protein-related disorders.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
No special preparation is needed for this test. However, inform your healthcare provider about any medications you are taking, as some may affect results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy