Serum Hemoglobin Electrophoresis (for Alpha-1 Antitrypsin and Related Proteins)
This test measures the distribution of hemoglobin variants and proteins in your blood, including Alpha-1 Antitrypsin, which helps assess conditions affecting red blood cells or protein metabolism.
["This test helps identify potential genetic or acquired blood disorders by examining protein patterns in your blood sample."]
Key facts at a glance
- LOINC
- 4590-6
- Short code
- Hgb Hashar Bld Ql Elph Alk
- Synonyms
- Hgb Hashar Bld Ql Elph Alk
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 3.5
- Ref high
- 5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis-ph
- CPT
- 84132
- SNOMED
- 110742001
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
This test measures the levels of specific substances in your blood, helping your doctor evaluate how well certain organs and body systems are working and identify potential health concerns.
The test uses electrophoresis to separate hemoglobin and other blood proteins based on their electrical charge. This helps identify abnormal hemoglobin forms or protein levels that may indicate conditions like sickle cell disease, thalassemia, or hereditary hemolytic anemia.
Your doctor may order this test to help diagnose a medical condition, monitor an ongoing health problem, or check how well your current treatment plan is working for you.
Your healthcare provider may order this test if you have symptoms like fatigue, anemia, or unexplained blood abnormalities. It’s also used in research or screening for inherited blood disorders.
A trained healthcare professional will collect a small sample, typically a blood draw from a vein in your arm, and the entire collection process usually takes only a few minutes.
A blood sample is drawn from a vein, typically in your arm. The sample is processed to separate serum for testing.
Most people can follow their normal daily routine before this test, but it is always a good idea to confirm any specific instructions with your doctor ahead of time.
No special preparation is needed for this test, and fasting is generally not required unless your doctor has specifically instructed you not to eat or drink beforehand.
Reference range
Adult: 3.5-5.0 mmol/LN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal results may indicate genetic disorders (e.g., alpha-1 antitrypsin deficiency), hemoglobinopathies (e.g., sickle cell trait), or other blood-related conditions. This test supports diagnosis and management of inherited or acquired blood disorders.
Short name
Hemoglobin Electrophoresis
Frequently asked questions
What does an abnormal result mean?
How long does it take to get results?
Is this test painful?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy