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Hemoglobin Inclusion Body Detection in Whole Blood

Published: August 9, 2026Updated: August 16, 2026

This test checks for abnormal protein structures called inclusion bodies within red blood cells, which may indicate certain blood disorders or genetic conditions.

Quick summary

["Inclusion bodies in red blood cells can signal underlying health concerns that may require further medical evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
59185-9
Short code
Hgb H inclusion bodies Bld Ql
Synonyms
Hgb H inclusion bodies Bld Ql
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, anemia, or unexplained red blood cell abnormalities, or if you have a family history of hemoglobinopathies or other blood disorders.

What to Expect During the Test

A small blood sample will be drawn from a vein in your arm. The sample is processed to detect any abnormal inclusion bodies in your red blood cells.

What the Results Mean

Positive results suggest the presence of abnormal protein structures that may need further diagnostic testing, such as genetic counseling or specialized blood tests.

Next Steps and Follow-Up

If results are positive, your doctor may recommend additional tests, such as genetic testing or a consultation with a hematologist to determine the cause and appropriate treatment.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Hemoglobin Inclusion Bodies Can Indicate Underlying Conditions

Short name

Hemoglobin Inclusion Body Screen (bld)

Frequently asked questions

Hemoglobin inclusion bodies are often associated with hereditary blood disorders like sickle cell disease variants or other hemoglobinopathies, which can affect oxygen transport and lead to complications like anemia or organ damage.
This test helps identify these conditions early, allowing for timely interventions, such as genetic counseling, lifestyle adjustments, or targeted treatments.
How Often Should This Test Be Done?
The frequency depends on your symptoms, medical history, and recommendations from your healthcare provider. Some people may need periodic monitoring if they have a known risk for hemoglobinopathies.
What Are Common Symptoms That Might Lead to This Test?
Symptoms such as persistent fatigue, unusual weakness, pale or yellowish skin, frequent infections, or swelling in limbs could prompt this test, especially if other blood tests show abnormalities.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy