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Serum Hemoglobin Electrophoresis (for Hemoglobin Fraction Analysis)

Published: August 9, 2026Updated: August 16, 2026

This test measures different types of hemoglobin in your blood using electrophoresis, a method that separates hemoglobin variants based on their electrical charge.

Quick summary

["Helps identify unusual hemoglobin forms that may relate to genetic conditions or blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71862-7
Short code
Hgb H MFr.DF Bld Elph
Synonyms
Hgb H MFr.DF Bld Elph
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is This Test Measuring?

Electrophoresis separates hemoglobin into its components—such as hemoglobin A, A2, F, and variants—by applying an electric current. This helps detect abnormal hemoglobin forms that might not be visible on standard blood tests.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like anemia, fatigue, or unusual blood test results, or if you have a family history of conditions like sickle cell disease or thalassemia.

Common Conditions Linked to Abnormal Findings

Abnormal hemoglobin patterns can signal genetic blood disorders (e.g., sickle cell trait, thalassemia) or other conditions affecting red blood cell structure.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate hemoglobin components for analysis.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Hemoglobin Electrophoresis

Frequently asked questions

Abnormal hemoglobin electrophoresis may indicate hereditary blood disorders that require monitoring or treatment, such as sickle cell disease or alpha/beta thalassemia.
This test helps confirm or rule out genetic conditions that can cause chronic fatigue, pain, or anemia. Early detection may guide treatment decisions.
How long does it take to get results?
Results are typically available within 24–72 hours, depending on lab processing times. Your doctor will discuss findings during your follow-up.
What are the typical reference ranges?
Reference ranges vary by lab and may not include specific numeric values for all hemoglobin fractions. Your doctor will interpret results in the context of your health.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy