Hemoglobin Electrophoresis (Serum/Plasma)
This test separates different types of hemoglobin in your blood using electrophoresis to help identify conditions affecting hemoglobin structure, such as sickle cell disease or other hemoglobinopathies.
["Helps diagnose and monitor blood disorders linked to abnormal hemoglobin."]
Key facts at a glance
- LOINC
- 4598-9
- Short code
- Hgb J-Oxf Bld Ql Elph Acid
- Synonyms
- Hgb J-Oxf Bld Ql Elph Acid
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis-ph
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Electrophoresis is a technique that uses an electric field to move different hemoglobin variants apart based on their electrical charge. This allows healthcare providers to detect variations in hemoglobin composition that may indicate inherited blood disorders.
Why It’s Done
Doctors may order this test if you have symptoms like fatigue, pain, frequent infections, or anemia, or if you have a family history of hemoglobin disorders. It’s also used to confirm diagnoses such as sickle cell trait or disease.
Sample Collection
A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate serum or plasma for testing.
Preparation for the Test
No special preparation is needed unless instructed by your healthcare provider. You may be asked to fast or avoid certain medications, but this is rare for this specific test.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal hemoglobin patterns can indicate genetic blood disorders like sickle cell disease, thalassemia, or other hemoglobinopathies. These conditions can affect how your blood carries oxygen, leading to symptoms like anemia, pain, or organ damage. Early detection and management are crucial for improving quality of life and preventing complications.
Short name
Hb Electrophoresis
Frequently asked questions
What does an abnormal result mean?
How long does it take to get results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy