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Hemoglobin A1c (HbA1c) with Electrophoresis

Published: August 9, 2026Updated: August 16, 2026

This test measures the percentage of hemoglobin A1c in your blood, which reflects your average blood sugar levels over the past 2–3 months. The electrophoresis portion helps separate different types of hemoglobin variants.

Quick summary

["HbA1c helps track long-term blood sugar control, while electrophoresis provides additional insight into hemoglobin structure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35125-4
Short code
Hgb Lepore MFr Bld
Synonyms
Hgb Lepore MFr Bld
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to monitor diabetes management, assess blood sugar trends, or investigate unusual hemoglobin patterns. HbA1c is particularly useful for patients with diabetes to avoid frequent blood sugar fluctuations.

How Is the Sample Collected?

A small blood sample is drawn from your arm, typically in a vein. The test may require additional processing to separate hemoglobin types via electrophoresis.

What Does the Result Mean?

The HbA1c percentage indicates average blood sugar levels, while electrophoresis results identify any abnormal hemoglobin variants (e.g., sickle cell trait). Results are interpreted by your provider based on clinical context.

Common Causes of Abnormal Results

Elevated HbA1c often signals uncontrolled diabetes, while abnormal electrophoresis may reveal genetic hemoglobin disorders (e.g., thalassemia, sickle cell disease). Other factors like anemia or blood loss can also affect results.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HbA1c Electrophoresis

Frequently asked questions

What questions might I have about this test?
This test helps diagnose diabetes and assess long-term blood sugar control. Electrophoresis provides extra details about hemoglobin composition, which can be important for diagnosing inherited blood disorders.
How often should I get this test?
Frequency depends on your health status. People with diabetes typically get HbA1c tested every 3–6 months, while others may need it less often or more frequently based on their condition.
Can I eat or drink before this test?
For standard HbA1c testing, fasting is not required. However, if electrophoresis is part of the test, follow any specific instructions your lab provides, as they may involve dietary restrictions or timing for sample processing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy