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Hemoglobin Mass Measurement (Whole Blood)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of hemoglobin in your red blood cells, which carries oxygen throughout your body. It helps assess your blood’s ability to transport oxygen efficiently.

Quick summary

["This test helps diagnose or monitor conditions affecting red blood cells and oxygen delivery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110885-1
Short code
Hgb Msmt Bld
Synonyms
Hgb Msmt Bld
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like fatigue, shortness of breath, pale skin, or unusual weakness. It’s also used to check for conditions such as anemia, blood loss, or other blood disorders. Sometimes, it’s included in routine blood work or during evaluations for suspected blood-related issues.

What Does the Test Involve?

A small blood sample is taken from a vein, usually in your arm. The sample is processed to measure the total hemoglobin content in your red blood cells. This test does not require fasting and can be done at the same time as other blood tests.

What Are Common Uses?

Hemoglobin mass measurement is primarily used to evaluate the overall health of your red blood cells and oxygen-carrying capacity. It can help diagnose types of anemia, monitor chronic diseases like heart failure or kidney disease, or assess the effectiveness of treatments for blood disorders.

What Might Affect Results?

Several factors can influence hemoglobin levels, including recent blood loss, dehydration, certain medications (like blood thinners or iron supplements), pregnancy, or chronic illnesses. If you’re unsure about any medications or conditions, discuss them with your healthcare provider before the test.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Hemoglobin Mass Test

Frequently asked questions

What does a low or high hemoglobin mass mean?
Low hemoglobin mass (anemia) may indicate insufficient red blood cells or hemoglobin production, which can cause fatigue, weakness, or pale skin. High hemoglobin mass (polycythemia) might suggest overproduction of red blood cells, potentially linked to conditions like dehydration, lung disease, or certain cancers. Your provider will interpret results in the context of your overall health and symptoms.
How often should I get this test?
The frequency depends on your health status. Routine blood tests may include this measurement, but your provider will determine how often it’s needed based on your medical history, symptoms, or treatment plan.
Can I prepare for this test?
No special preparation is usually required. However, inform your healthcare provider about any medications, recent blood donations, or illnesses you’ve had before the test to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy