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Hemoglobin Mass Measurement by Flow Cytometry (Whole Blood)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of hemoglobin in your red blood cells, which carries oxygen throughout your body. It helps assess overall red blood cell health and potential blood disorders.

Quick summary

["This test helps doctors check if you have enough healthy red blood cells and oxygen-carrying capacity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109887-0
Short code
Hgb Msmt BldMV
Synonyms
Hgb Msmt BldMV
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Hemoglobin is the protein in red blood cells that binds and transports oxygen from your lungs to the rest of your body. Low levels can indicate anemia, blood loss, or other conditions affecting red blood cell production or function. This test provides a precise count of hemoglobin mass, which can help diagnose or monitor conditions like iron deficiency, chronic illness, or blood disorders.

When You Might Need It

Your doctor may order this test if you have symptoms like fatigue, pale skin, shortness of breath, or dizziness. It’s also used during pregnancy, before surgeries, or to monitor conditions like anemia, kidney disease, or certain cancers.

Sample Collection and Preparation

A small blood sample is drawn from a vein in your arm. The blood is analyzed immediately using flow cytometry, a technique that separates and counts red blood cells while measuring their hemoglobin content without needing separate hemoglobin testing.

What to Expect Before the Test

No special preparation is needed, but inform your doctor about any medications, recent blood donations, or conditions that might affect results (e.g., recent blood loss, certain medications). Avoid strenuous activity 24 hours before the test if possible.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Hemoglobin Mass Test

Frequently asked questions

What does a low or high hemoglobin mass mean?
Low hemoglobin mass (anemia) may signal iron deficiency, chronic disease, or blood loss. High levels could indicate polycythemia (too many red blood cells) or dehydration. Your doctor will interpret results in the context of your symptoms, medical history, and other tests.
How does this test differ from traditional hemoglobin tests?
This test measures total hemoglobin mass directly in whole blood, providing a more accurate count of red blood cells’ oxygen-carrying capacity. Traditional hemoglobin tests (like hemoglobin A1c) measure a different component or use separate methods (e.g., colorimetric assays).
Can I fast before this test?
No fasting is required, but avoid heavy meals or alcohol 24 hours before to ensure accurate results. If you’re on blood thinners or have a history of clotting issues, let your doctor know.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy