Serum Protein Electrophoresis (Qualitative)
This test measures the different types of proteins in your blood using electrophoresis, a method that separates proteins based on size and charge. It helps identify abnormalities in protein distribution, which may indicate conditions like multiple myeloma, liver disease, or other disorders.
["This test helps doctors diagnose and monitor protein-related blood disorders by showing how proteins are distributed in your serum."]
Key facts at a glance
- LOINC
- 4616-9
- Short code
- Hgb N-Seattle Bld Ql Elph Alk
- Synonyms
- Hgb N-Seattle Bld Ql Elph Alk
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 3.5
- Ref high
- 5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis-ph
- CPT
- 84132
- SNOMED
- 110742001
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Electrophoresis separates proteins into bands based on their electrical charge and molecular weight. The test detects abnormal protein patterns, such as monoclonal spikes (e.g., M proteins) or altered albumin/globulin ratios, which can signal conditions like plasma cell dyscrasias or chronic liver disease.
Why Might Your Doctor Order This Test?
Your doctor may recommend this test if you have symptoms like unexplained weight loss, fatigue, bone pain, or signs of liver/kidney disease. It’s also used to monitor treatment progress in conditions like multiple myeloma or lymphoma.
Common Conditions Linked to Abnormal Results
Abnormal results may suggest conditions like multiple myeloma (excess monoclonal proteins), chronic liver disease (altered albumin/globulin ratios), or inflammatory disorders. Mild abnormalities may require further testing or follow-up.
What to Expect Before or After the Test
No special preparation is needed. A blood sample is drawn from a vein, usually in your arm. The process takes about 15 minutes. Results are typically ready within 24–48 hours.
Reference range
Adult: 3.5-5.0 mmol/LN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Interpretation and Next Steps
Short name
Qual Serum Protein Electrophoresis
Frequently asked questions
How long will I need to wait for results?
What if my results are abnormal?
Is fasting required for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy