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Hemoglobin A1c (HbA1c) with mass concentration measurement by high-performance liquid chromatography (HPLC)

Published: August 9, 2026Updated: August 16, 2026

This test measures the average level of hemoglobin A1c in your blood over the past 2–3 months, reflecting your blood sugar control during that time.

Quick summary

["HbA1c helps doctors track diabetes management and adjust treatment plans."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54068-2
Short code
Hgb O-Arab MFr DBS
Synonyms
Hgb O-Arab MFr DBS
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What HbA1c Measures

HbA1c is a form of hemoglobin (the protein in red blood cells that carries oxygen) that has been linked to glucose (sugar) over time. It’s a reliable indicator of how well your blood sugar has been controlled during this period.

How It’s Used in Care

Healthcare providers use HbA1c to assess long-term blood sugar levels, helping to diagnose diabetes, monitor treatment effectiveness, and prevent complications like nerve damage or kidney disease.

Why It Matters for You

Regular HbA1c testing is crucial for people with diabetes or prediabetes to stay on track with lifestyle and medication changes that keep blood sugar stable.

What to Expect Before the Test

No special preparation is needed. A small blood sample is taken from your arm, similar to a routine blood draw. The test is quick and painless.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: HbA1c is a gold-standard marker for chronic blood sugar management. Values above or below reference ranges may signal poor control, undiagnosed diabetes, or other metabolic conditions requiring further evaluation.

Short name

HbA1c

Frequently asked questions

Why might my HbA1c be checked?
Your doctor may order this test if you have diabetes, prediabetes, or if you’re at risk for developing it. It’s also used to evaluate how well your current treatments are working.
What do my HbA1c results mean?
Results are typically reported as a percentage. A lower percentage may indicate better blood sugar control, while a higher percentage suggests more frequent blood sugar spikes or poor management.
Can HbA1c results change over time?
Yes, HbA1c levels can shift with diet, exercise, medications, or underlying health changes. Regular monitoring helps track these trends and adjust care as needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy