Hemoglobin Mass Fraction in Whole Blood (Thermal Stability-Based Method)
This test measures the amount of hemoglobin in your blood, focusing on its stability under heat. It may be used to assess conditions affecting red blood cell structure or function.
["Helps evaluate red blood cell health and potential blood disorders."]
Key facts at a glance
- LOINC
- 48343-8
- Short code
- Hgb Other MFr Bld
- Synonyms
- Hgb Other MFr Bld
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like fatigue, pale skin, shortness of breath, or unexplained anemia. It could also be part of a broader evaluation for conditions like sickle cell disease, thalassemia, or other hemoglobinopathies.
What to Expect Before the Test
No special preparation is needed. You’ll typically have a small needle inserted into your arm or hand to draw a blood sample. The test involves heating the blood sample to assess hemoglobin stability.
What the Results Mean
Results may indicate whether your hemoglobin is stable or if there are changes in its structure that could affect blood function. Abnormal findings might prompt further testing or follow-up.
Common Conditions Monitored
This test helps diagnose or monitor conditions like hereditary hemolytic anemia, certain hemoglobin disorders, or other blood-related issues where red blood cell stability is important.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Hemoglobin Stability Test
Frequently asked questions
What does a high or low result mean?
Does this test replace standard hemoglobin tests?
Your healthcare provider will determine the frequency based on your medical history, symptoms, and treatment plan. Regular monitoring may be recommended if you have a known hemoglobin disorder or related condition.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy