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Hemoglobin Electrophoresis (Therapeutic Monitoring of Blood)

Published: August 9, 2026Updated: August 16, 2026

This test analyzes the types of hemoglobin in your blood, often used to monitor conditions like sickle cell disease or other hemoglobinopathies.

Quick summary

["Helps track how well your blood hemoglobin types are responding to treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32017-6
Short code
Hgb Other MFr Bld Elph
Synonyms
Hgb Other MFr Bld Elph
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Hemoglobin electrophoresis separates different hemoglobin variants based on their electrical charge. This helps identify abnormal hemoglobin forms, such as sickle hemoglobin (HbS) or other variants that may cause blood disorders.

Why It’s Done

Doctors may order this test if you have a genetic blood disorder, symptoms like fatigue, pain from blood clumps, or if you’re being treated for conditions like sickle cell disease.

Sample Collection

A small blood sample is drawn from a vein, typically in your arm. The sample is then processed to analyze hemoglobin types using gel electrophoresis.

Preparation & Results

No special preparation is needed, but fasting isn’t required. Results show the proportion of different hemoglobin types, helping doctors assess your condition and treatment effectiveness.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Hemoglobin Electrophoresis

Frequently asked questions

This test is critical for diagnosing and managing hemoglobinopathies, ensuring proper treatment and monitoring disease progression or response to therapy.
This test helps identify abnormal hemoglobin forms that may cause health issues like anemia, pain crises, or other complications. It’s especially important for patients with inherited blood disorders.
How long will I need to wait for results?
Results are typically available within 1–3 business days, depending on lab processing times. Your doctor will discuss them with you during your follow-up visit.
Can I eat or drink before this test?
No special diet is required. You can eat and drink normally before the blood draw, as it doesn’t affect the test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy