Hemoglobin concentration in plasma (measured by mass concentration)
This test measures the amount of hemoglobin, the protein in red blood cells that carries oxygen, in your plasma. It can help assess blood health and detect conditions like anemia or bleeding disorders.
["Helps diagnose or monitor blood-related conditions by checking hemoglobin levels in plasma."]
Key facts at a glance
- LOINC
- 35183-3
- Short code
- Hgb Plas-msCnc
- Synonyms
- Hgb Plas-msCnc
- Category
- hematology
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is Plasma Hemoglobin Used For?
Plasma hemoglobin testing is primarily used to evaluate conditions affecting red blood cells or blood volume. It may be ordered to investigate symptoms like fatigue, pale skin, or signs of excessive bleeding. In some cases, it can also help monitor patients undergoing treatments that affect red blood cell production or integrity.
When Might You Need This Test?
Your healthcare provider might recommend this test if you have symptoms such as unusual tiredness, shortness of breath, pale or yellowish skin, easy bruising, or unexplained bleeding. It may also be part of a broader evaluation for conditions like anemia, hemolytic disorders, or severe trauma.
How Is the Test Performed?
A small blood sample is drawn from a vein, usually in your arm. The blood is then separated into plasma and red blood cells. The hemoglobin concentration in the plasma is measured using a specialized laboratory technique.
What Are the Results?
Results are typically reported as a mass concentration value (e.g., grams per liter). While reference ranges can vary by lab, abnormal results may indicate conditions affecting red blood cells or blood volume. Your healthcare provider will interpret the results in the context of your overall health and symptoms.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Plasma hemoglobin
Frequently asked questions
Why is this test important in diagnosing or managing health conditions?
What does a high plasma hemoglobin level mean?
What does a low plasma hemoglobin level mean?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy