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Hemoglobin Mass Concentration in Whole Blood

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of hemoglobin (the protein in red blood cells that carries oxygen) in your blood.

Quick summary

["Helps assess red blood cell function and potential anemia."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
722-9
Short code
Hgb Plr-mCnc
Synonyms
Hgb Plr-mCnc
Category
hematology
Sample
fluid
Container
Sterile tube
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What Is Hemoglobin?

Hemoglobin is the molecule in red blood cells responsible for transporting oxygen from your lungs to the rest of your body. It also carries carbon dioxide away from tissues back to the lungs. Hemoglobin levels can give important clues about whether your red blood cells are healthy or if there may be a blood disorder.

Why Might This Test Be Ordered?

Your healthcare provider may order this test to evaluate symptoms like fatigue, pale skin, shortness of breath, or unusual weakness. It can also be part of routine blood work, monitoring for conditions like anemia, blood loss, or certain genetic disorders.

How Is the Test Performed?

A small sample of your blood is drawn from a vein, usually in your arm. The blood is then analyzed in a lab to measure the total hemoglobin mass concentration.

What Does a Low or High Hemoglobin Level Mean?

Hemoglobin levels can vary based on factors like age, sex, and overall health. Low levels may suggest anemia or blood loss, while very high levels could indicate conditions like polycythemia (too many red blood cells). Your results will be compared to your specific health profile and symptoms.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: fluid

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Hemoglobin Mass

Frequently asked questions

How does this test help diagnose or monitor conditions?
This test helps diagnose anemia by confirming whether red blood cells are producing enough hemoglobin. It can also help monitor conditions like chronic kidney disease, blood loss from bleeding disorders, or certain cancers. Hemoglobin mass concentration is particularly useful in detecting iron-deficiency anemia, where iron is needed to produce hemoglobin.
What are the typical reference ranges for this test?
Reference ranges are not provided here because they vary widely by lab, age, sex, and individual health. Your healthcare provider will interpret your results in the context of your overall health and symptoms.
Can this test be done at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy