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Hemoglobin A1c (HbA1c) measured by high-performance liquid chromatography (HPLC)

Published: August 9, 2026Updated: August 16, 2026

This test measures the average level of hemoglobin A1c in your blood over the past 2–3 months, reflecting your blood sugar control.

Quick summary

["HbA1c helps doctors assess long-term diabetes management and adjust treatment plans."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
723-7
Short code
Hgb Prt-mCnc
Synonyms
Hgb Prt-mCnc
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is HbA1c Used For?

HbA1c is primarily used to diagnose diabetes, monitor blood sugar levels over time, and evaluate how well diabetes treatments are working. It’s a key indicator of your body’s ability to manage glucose (sugar) in the blood, even if your current blood sugar levels are normal.

How Is HbA1c Different from Daily Blood Sugar Checks?

Unlike daily blood sugar tests (like fingerstick glucose checks), HbA1c gives a broader picture of your average blood sugar over months. It accounts for fluctuations that daily tests might miss, making it a reliable measure for long-term health.

Why Is HbA1c Important for People Without Diabetes?

Even if you don’t have diabetes, HbA1c can help identify prediabetes or early signs of blood sugar issues. Regular monitoring can help prevent complications like nerve damage or heart disease.

How Often Should I Get an HbA1c Test?

Doctors typically recommend HbA1c testing every 3–6 months for people with diabetes. Others may test annually or as advised by their healthcare provider, depending on risk factors.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

HbA1c is a critical tool for diagnosing diabetes (when levels are ≥6.5%) and assessing prediabetes (4.0%–5.6%). Lower-than-normal levels (below 5.7%) suggest good blood sugar control. Repeatedly high or low HbA1c can signal underlying conditions like insulin resistance or poor medication adherence, guiding necessary lifestyle or treatment changes.

Short name

HbA1c

Frequently asked questions

What Does an HbA1c Test Involve?
The test requires a small blood sample (like a fingerstick) and is processed using HPLC to measure the percentage of hemoglobin bound to glucose. Results are expressed as a percentage (e.g., 5.8% is considered prediabetes).
How Does HbA1c Compare to Other Blood Sugar Tests?
Unlike fasting or random blood sugar tests, HbA1c doesn’t depend on timing or diet. It’s a stable measure of long-term glucose exposure, making it more consistent for tracking trends over time.
Can HbA1c Results Be Affected by Other Factors?
Yes, factors like anemia, kidney disease, or certain medications (e.g., iron supplements) can slightly alter HbA1c results. Always discuss your full medical history with your doctor to interpret results accurately.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy