Hemoglobin Subtype Analysis by Electrophoresis (Serum/Plasma)
This test measures different types of hemoglobin in your blood, which can help identify conditions like sickle cell disease or other hemoglobinopathies.
["This test helps diagnose blood disorders by checking for unusual hemoglobin patterns."]
Key facts at a glance
- LOINC
- 6864-3
- Short code
- Hgb S Bld Ql Soly
- Synonyms
- Hgb S Bld Ql Soly
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- solubility-test
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Hemoglobin is the protein in red blood cells that carries oxygen. Certain genetic conditions cause variations in hemoglobin structure, which this test detects. The electrophoresis method separates hemoglobin types based on their electrical charge, revealing any abnormal forms.
Why It’s Done
Your healthcare provider may order this test if you have symptoms like fatigue, pain, or frequent infections, or if you have a family history of blood disorders. It’s also used in newborn screening for conditions like sickle cell anemia.
Sample Collection and Preparation
A blood sample is taken from a vein, usually in your arm. The blood is processed to separate serum or plasma, where hemoglobin types are analyzed using an electrophoresis technique that sorts proteins by size and charge.
What to Expect Before the Test
No special preparation is needed, but inform your provider about any medications or recent blood transfusions. Avoid strenuous activity 24 hours before testing if possible.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal hemoglobin patterns may indicate genetic disorders like sickle cell disease, thalassemia, or other hemoglobinopathies. Early detection can guide treatment and management strategies, such as monitoring, medication, or lifestyle adjustments.
Short name
Hb Subtype Screening
Frequently asked questions
What does an abnormal result mean?
How long does it take to get results?
Can I fast before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy