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Serum or Plasma Protein Electrophoresis by Bromocresol Green

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of proteins in your blood using electrophoresis and a dye called bromocresol green. It helps identify abnormal protein patterns, which may indicate conditions like multiple myeloma, liver disease, or other disorders.

Quick summary

["This test helps doctors spot unusual protein levels that could signal serious health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12712-6
Short code
Hgb S+D+G Reg Bld Ql Elph Alk
Synonyms
Hgb S+D+G Reg Bld Ql Elph Alk
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
3.5
Ref high
5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis-ph
CPT
84132
SNOMED
110742001
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Protein electrophoresis separates blood proteins into different fractions (e.g., albumin, globulins) based on size and charge. Bromocresol green binds to proteins, allowing visual differentiation of these fractions. This helps detect shifts in protein composition that may reflect underlying diseases.

Common Uses and Indications

Doctors may order this test to diagnose or monitor conditions such as multiple myeloma, chronic liver disease, or certain autoimmune disorders. It’s also used in screening for protein abnormalities in kidney disease or after chemotherapy.

How the Test Works

A small blood sample is drawn, and proteins are separated using an electric field. The dye binds to specific protein types, creating distinct bands. These bands are analyzed to compare protein levels to what’s expected in healthy blood.

Preparation and Sample Collection

No special preparation is needed, but fasting may be advised depending on the lab’s protocol. A simple blood draw is performed, and the sample is sent to the lab for processing.

Reference range

Adult: 3.5-5.0 mmol/LN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCG Protein Electrophoresis

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you have symptoms like unexplained weight loss, fatigue, swollen lymph nodes, or signs of organ dysfunction. It’s also used to track treatment responses in conditions like multiple myeloma or liver disease.
What do abnormal results mean?
Abnormal patterns may show too much or too little of certain proteins. For example, high levels of abnormal proteins could indicate myeloma, while altered albumin/globulin ratios might suggest liver or kidney issues. Always discuss results with your healthcare provider.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Follow-up with your doctor to interpret the findings and plan next steps.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy