Hemoglobin Subtype Mass Fraction by Electrophoresis (Serum)
This test measures the different types of hemoglobin in your blood using electrophoresis, a method that separates hemoglobin variants based on their electrical charge.
["Helps identify abnormal hemoglobin forms that may indicate genetic conditions or blood disorders."]
Key facts at a glance
- LOINC
- 4625-0
- Short code
- Hgb S MFr Bld
- Synonyms
- Hgb S MFr Bld
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 12
- Ref high
- 17.5
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85018
- SNOMED
- 900000000000003004
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Electrophoresis separates hemoglobin into bands, each representing a specific type of hemoglobin (e.g., hemoglobin A, A2, F, S, C, or others). The mass fraction percentages of these subtypes are recorded for analysis.
Why It’s Ordered
Your healthcare provider may order this test if you have symptoms like fatigue, anemia, or unexplained blood abnormalities, or if you have a family history of hemoglobin disorders such as sickle cell disease or thalassemia.
Common Conditions Linked to Abnormal Results
Abnormal hemoglobin patterns can signal genetic blood disorders (e.g., sickle cell trait, sickle cell disease, or hereditary spherocytosis) or conditions like polycythemia vera or certain types of anemia.
Sample Collection and Preparation
A blood sample is drawn from a vein in your arm. The blood is processed to separate serum, where hemoglobin subtypes are analyzed using electrophoresis.
Reference range
Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal hemoglobin profiles are critical for diagnosing inherited blood disorders that can affect oxygen transport in your body. Early detection allows for targeted treatment and management strategies to improve quality of life and prevent complications.
Short name
Hemoglobin Electrophoresis Profile
Frequently asked questions
What does an abnormal result mean?
How long does it take to get results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy