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Gastrointestinal Tract Specific Protein Profile (Qualitative Screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures specific proteins found in stool samples to help identify potential issues in the gastrointestinal tract, such as inflammation, infection, or bleeding.

Quick summary

["A qualitative stool protein test can help detect abnormalities in your digestive system that may require further medical evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42910-0
Short code
Hgb sp2 Gast gastro Ql
Synonyms
Hgb sp2 Gast gastro Ql
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test detects the presence of certain proteins in stool that may originate from the gastrointestinal lining, blood, or other sources. Proteins like hemoglobin fragments, mucin, or other biomarkers are analyzed to assess for conditions such as gastrointestinal bleeding, inflammation, or infection.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like unexplained weight loss, persistent diarrhea, black or tarry stools, abdominal pain, or if you have a history of gastrointestinal issues. It can also be used as part of a broader evaluation for conditions like ulcerative colitis, Crohn’s disease, or gastrointestinal bleeding.

Sample Collection and Preparation

A stool sample is collected, typically through a simple at-home collection kit provided by your healthcare provider. The sample is then sent to the lab for analysis. No special preparation is usually needed, but you may be advised to avoid certain foods or medications for a few days before testing.

What to Expect During Testing

The test is non-invasive and does not require a blood draw or other invasive procedures. Results are generally processed within a few days, and your healthcare provider will discuss them with you during your follow-up visit.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results for specific proteins in stool may indicate conditions such as gastrointestinal bleeding, inflammatory bowel disease, or infections. Negative results do not definitively rule out these conditions, so further diagnostic testing may still be needed. Your doctor will interpret results in the context of your symptoms and medical history.

Short name

Gastrointestinal Protein Screen (Qualitative)

Frequently asked questions

What does a positive result mean?
A positive result suggests the presence of certain proteins in your stool that may point toward gastrointestinal bleeding, inflammation, or infection. This finding will need to be evaluated by your healthcare provider to determine the next steps, which could include additional tests or treatments.
How soon will I get my results?
Results are typically available within a few days to a week, depending on the lab’s processing time. Your healthcare provider will contact you to discuss the findings once they are ready.
Can I eat or drink normally before this test?
You may follow a standard diet unless instructed otherwise by your provider. Some tests may require specific dietary restrictions for a few days before collection, but this test does not typically have such requirements.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy