Hemoglobin S Penetrance Screening (Serum) – Gastric Acid Lowering Quality Indicator Assessment
This test is part of a screening process to assess how hemoglobin S (the abnormal form of hemoglobin found in sickle cell disease) may interact with gastric acid levels, though the exact purpose is not a standard clinical measurement. It may be used in research or specialized diagnostic contexts.
["This test helps evaluate potential genetic or biochemical interactions that could affect blood health and gastrointestinal function."]
Key facts at a glance
- LOINC
- 56491-4
- Short code
- Hgb sp3 Stl gastro lower Ql IA
- Synonyms
- Hgb sp3 Stl gastro lower Ql IA
- Category
- hematology
- Sample
- stool
- Container
- Clean container
- Units
- N/A
- Ref low
- 10
- Ref high
- 40
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 84484
- SNOMED
- 302774002
- Specimen volume
- 5 g
- Stability
- Refrigerated: 24h, Frozen: 7d
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
This test evaluates the presence or potential impact of hemoglobin S (a variant of hemoglobin) in relation to gastric acid levels, though the specific biochemical pathway or analyte is not a standard clinical test. It may involve measuring hemoglobin-related components in serum or plasma.
Why It Might Be Ordered
Your healthcare provider may order this test if there is suspicion of sickle cell trait or related conditions, or if research studies require assessment of hemoglobin S interaction with gastric acid. It may also be part of a broader evaluation for genetic or metabolic testing.
What to Expect Before the Test
No special preparation is typically required, but you may be asked to fast for a few hours if the test involves blood collection. Follow any specific instructions your provider gives you.
What to Expect During the Test
A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the procedure is quick. If you have a history of blood draw discomfort, let your provider know.
Reference range
Adult: 10-40 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is not a standard diagnostic tool for sickle cell disease or gastric acid disorders. It may be used in specialized research settings or to investigate rare genetic interactions. Results should be interpreted by a healthcare professional familiar with the specific context of the test.
Short name
Hemoglobin S Screening (Serium) – Gastric Acid Test
Frequently asked questions
Why might my doctor order this test?
What does a positive or abnormal result mean?
Do I need to do anything special after the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy