Hemoglobin and Red Blood Cell Electrophoresis (Serum/Plasma)
This test measures the types and amounts of proteins in your red blood cells, including hemoglobin variants, using electrophoresis. It helps identify conditions affecting red blood cell structure or function.
["This test helps diagnose blood disorders like sickle cell disease or other hemoglobinopathies."]
Key facts at a glance
- LOINC
- 53117-8
- Short code
- Hgb TL RBC Ql
- Synonyms
- Hgb TL RBC Ql
- Category
- hematology
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 7 N/A – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Electrophoresis separates proteins in your blood based on size and electrical charge. In this test, we analyze hemoglobin and red blood cell components to identify any abnormal patterns or concentrations that may indicate inherited or acquired blood disorders.
Why It’s Done
Your doctor may order this test if you have symptoms like fatigue, pale skin, unusual pain, or a family history of blood disorders. It’s also used to screen for conditions like sickle cell disease, thalassemia, or other hemoglobin-related issues.
How It Works
A small blood sample is drawn, and the serum/plasma is separated. Proteins are then placed on a gel and exposed to an electric current, causing them to move at different speeds. A specialized instrument detects and measures the distribution of these proteins.
Sample Collection
A needle is used to draw blood from a vein in your arm. The sample is processed to isolate serum or plasma for analysis. This process is quick and typically done in a clinical setting.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal results may indicate inherited blood disorders (e.g., sickle cell anemia, thalassemia), metabolic issues, or other conditions affecting red blood cell proteins. Early detection can guide treatment and management strategies.
Short name
Hemoglobin & RBC Electrophoresis
Frequently asked questions
What does an abnormal result mean?
How long does it take to get results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy