Skip to content

Hemoglobin A1c (HbA1c) with 24-Hour Urine Collection for Quantitative Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures your body’s average blood sugar levels over the past 2–3 months, using both blood and urine samples. It helps assess long-term glucose control, particularly in patients suspected of having abnormal urine hemoglobin or related conditions.

Quick summary

["This test helps track how well your blood sugar is managed over time, especially if you have diabetes or suspected hemolytic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57751-0
Short code
Hgb Ur Ql Strip.auto
Synonyms
Hgb Ur Ql Strip.auto
Category
hematology
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
test-strip-automated
CPT
85018
SNOMED
900000000000003004
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of diabetes, hemolytic anemia, or unexplained urine changes. It’s also used to confirm or monitor conditions affecting red blood cell breakdown or glucose metabolism.

How the Test Works

A 24-hour urine sample is collected to measure hemoglobin-related substances. The test combines urine analysis with a standard HbA1c measurement to detect subtle metabolic or hemolytic disturbances that standard blood tests might miss.

What to Expect Before the Test

No special preparation is needed beyond collecting a full 24-hour urine sample (starting and ending at the same time). Drink plenty of water to ensure adequate urine volume. Avoid smoking or certain medications that may affect urine composition.

What to Expect During the Test

You’ll provide a urine sample at home or in a lab, following instructions to collect all urine for 24 hours. The sample is then analyzed to detect hemoglobin or related breakdown products.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is particularly useful for identifying hemolytic anemia (where red blood cells break down too quickly) or conditions like glucose-6-phosphate dehydrogenase (G6PD) deficiency, which can cause abnormal urine hemoglobin. It also helps assess chronic diabetes management by cross-referencing urine and blood glucose trends.

Short name

HbA1c Urine Test (24h)

Frequently asked questions

Why might my doctor recommend this test?
Your doctor may suggest this test if you have unexplained fatigue, dark urine, or symptoms of hemolysis (e.g., jaundice). It’s also used in research or specialized cases where standard HbA1c alone isn’t sufficient to diagnose or monitor a condition.
What does a positive or abnormal result mean?
An abnormal result may indicate hemolysis (red blood cell destruction), G6PD deficiency, or other metabolic disorders. Your doctor will discuss findings in the context of your symptoms and other lab results.
How often should I get this test?
Frequency depends on your health condition. If you have diabetes or suspected hemolytic anemia, your doctor may recommend it periodically to monitor progression or treatment effectiveness.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy