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Human Herpesvirus 6 IgG Antibody (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against Human Herpesvirus 6 (HHV-6) in your blood. Antibodies are your body’s natural defense against infections.

Quick summary

["This test helps determine if you’ve been exposed to HHV-6, a virus that can cause infections or reactivate in certain conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34946-4
Short code
HHV6 IgG+IgM Pnl CSF
Synonyms
HHV6 IgG+IgM Pnl CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgG antibodies, which develop after your body has been exposed to HHV-6. IgG antibodies are typically present long-term if you’ve had an infection or vaccination. This test is usually done to assess past exposure rather than active infection.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like fever, fatigue, or rash that could be linked to HHV-6, especially after a recent illness or transplant. It can also be used to monitor immune responses in certain medical conditions.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it is tested using an immunoassay method to detect HHV-6 antibodies.

What Are the Results Typically Used For?

Results help confirm past exposure to HHV-6, which can inform treatment decisions, especially in patients with weakened immune systems or those undergoing medical procedures that increase infection risk.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HHV-6 IgG Antibody

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 24 to 72 hours, depending on your lab’s processing schedule. Your healthcare provider will contact you once they have the results.
Can this test detect an active HHV-6 infection?
No, this test specifically measures IgG antibodies, which indicate past exposure rather than an active infection. If you suspect an active infection, other tests or clinical evaluation may be needed.
What do low or negative results mean?
A negative result means you likely have not been exposed to HHV-6 in the past, or your body has cleared the virus. A low or absent IgG level may also suggest recent exposure or a very early infection stage.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy