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Human Herpesvirus 8 (HHV-8) Antibody, Serum/Plasma (Qualitative Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of antibodies against Human Herpesvirus 8 (also called Kaposi’s sarcoma-associated herpesvirus) in your blood. Antibodies indicate your immune system has recognized and responded to this virus.

Quick summary

["This test helps determine if you’ve been exposed to HHV-8, which can be linked to certain cancers and infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97862-7
Short code
HHV8 IgG+IgM Pnl SerPl
Synonyms
HHV8 IgG+IgM Pnl SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions associated with HHV-8, such as Kaposi’s sarcoma (a rare cancer), certain lymphomas, or persistent infections. It may also be used in research or monitoring for patients at higher risk, like those with weakened immune systems or specific medical histories.

What to Expect Before the Test

No special preparation is needed for this test. You’ll provide a blood sample, usually drawn from your arm. If you’re on blood thinners or have a history of bleeding disorders, let your provider know before the test.

What the Test Results Mean

A positive result means your body has detected antibodies to HHV-8, suggesting past exposure. A negative result indicates no detectable antibodies at this time. Results alone don’t confirm active infection but can guide further evaluation if needed.

Common Conditions Monitored or Diagnosed With This Test

HHV-8 is often linked to Kaposi’s sarcoma, a type of cancer that can develop in people with weakened immune systems (e.g., due to HIV/AIDS, organ transplants, or certain chemotherapy treatments). This test helps assess exposure risk or monitor conditions where HHV-8 plays a role.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HHV-8 Antibody Screen

Frequently asked questions

Could I get this test if I don’t have symptoms?
Yes, your doctor might order this test even if you’re asymptomatic. It’s sometimes used in research studies, for screening high-risk groups (e.g., HIV-positive patients), or to evaluate unexplained symptoms like persistent skin rashes or lymph node swelling that could be linked to HHV-8.
What if my test is positive?
A positive result means you’ve likely been exposed to HHV-8, but it doesn’t always mean you’re currently infected. Follow-up testing (like PCR for viral DNA) may be needed to check for active infection. Your provider will discuss next steps based on your overall health and symptoms.
Does this test replace other tests for HHV-8-related conditions?
No, this antibody test is a screening tool. For diagnosing active HHV-8 infection or related diseases (like Kaposi’s sarcoma), your doctor may use additional tests, including viral load testing or biopsy of affected tissues. Always follow your healthcare team’s recommendations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy