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Plasma or serum measurement of protein concentration related to preeclampsia during pregnancy (e.g., proteinuria or specific protein markers)

Published: August 9, 2026Updated: August 17, 2026

This test helps monitor high blood pressure and protein in urine during pregnancy, which can signal preeclampsia—a serious condition requiring close medical attention.

Quick summary

["Early detection of preeclampsia may prevent complications for both mother and baby."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
58301-3
Short code
High BP WO toxemia during pregnancy
Synonyms
High BP WO toxemia during pregnancy
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
0.5 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done During Pregnancy

High blood pressure (hypertension) and protein in urine (proteinuria) during pregnancy can indicate preeclampsia, a condition that may lead to serious health risks if left untreated. This test measures protein levels in blood or urine to assess kidney function and blood vessel health in pregnancy.

What to Expect Before the Test

You may be asked to provide a urine sample (often a 24-hour collection) or a blood sample, depending on the specific protein marker being tested. Your healthcare provider will guide you on preparation, such as avoiding certain medications or dietary restrictions.

What the Results Mean

Elevated protein levels in urine or blood may signal early signs of preeclampsia. Your doctor will interpret results alongside other symptoms (e.g., swelling, headaches) and medical history to guide next steps, such as monitoring or treatment adjustments.

Common Causes or Risk Factors

Risk factors for preeclampsia include high blood pressure before pregnancy, chronic kidney disease, obesity, or a family history of the condition. Other contributing factors may include advanced maternal age or multiple pregnancies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Early detection of preeclampsia through protein testing helps prevent complications like seizures, organ damage, or preterm labor. Regular monitoring ensures timely intervention, such as medication, bed rest, or delivery planning to protect both mother and baby.

Short name

Pregnancy-related protein test

Frequently asked questions

How often will I need this test?
Your doctor will determine the frequency based on your pregnancy history, symptoms, and risk factors. Tests may be done weekly or more often during high-risk pregnancies.
What if my results are abnormal?
If results show elevated protein levels, your provider will discuss next steps, which may include additional tests, closer monitoring, or changes in care plan. Follow-up may involve blood pressure checks, ultrasounds, or hospital admission if needed.
Can I prevent preeclampsia?
While some risk factors cannot be changed, lifestyle changes like managing blood pressure, staying hydrated, and avoiding smoking may help reduce risk. Regular prenatal care is key to early detection and management.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy