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Immunoglobulin G (IgG) mass concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody found in your blood. IgG helps protect your body from infections by fighting bacteria and viruses.

Quick summary

["IgG helps fight infections and is a key part of your immune system."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63170-5
Short code
H interseminatum IgG-mCnc
Synonyms
H interseminatum IgG-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may order this test to check if your immune system is working properly. It can help diagnose or monitor conditions like low immunity, certain infections, or immune system disorders. It may also be used to evaluate responses to treatments or vaccinations.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample. If you’re nervous, let your healthcare provider know so they can help make it more comfortable.

What the Test Results Mean

Results are compared to a general range of what’s considered normal for IgG levels in blood. While reference ranges can vary slightly by lab, very low or very high levels may signal potential health concerns that need further evaluation.

Common Conditions Monitored

IgG levels are often checked in people with weakened immune systems, those recovering from infections, or those receiving treatments like chemotherapy. It can also be used to assess immune responses after vaccines.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

IgG is the most abundant antibody in your blood and plays a critical role in long-term immunity. Low IgG levels may indicate immune deficiencies, chronic infections, or malabsorption issues, while very high levels can sometimes be linked to autoimmune conditions or certain cancers. Your doctor will interpret results in the context of your overall health.

Short name

IgG Level

Frequently asked questions

What causes IgG levels to be checked?
IgG levels are checked if you have symptoms of a weakened immune system, such as frequent infections, slow wound healing, or unexplained fatigue. It may also be part of routine monitoring for people with certain medical conditions or those receiving treatments that affect immunity.
How long does it take to get test results?
Test results are typically available within a few days to a week, depending on your lab and healthcare provider. Your doctor will contact you once the results are ready to discuss them with you.
Can IgG levels change over time?
Yes, IgG levels can fluctuate due to infections, vaccinations, aging, or certain medical treatments. If your levels are abnormal, your doctor may recommend follow-up tests to understand the cause and guide treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy