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Multigene Panel Analysis for Hereditary Hemorrhagic Telangiectasia (HHT) via Whole Blood

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic mutations linked to hereditary hemorrhagic telangiectasia (HHT), a rare condition that affects blood vessels and can cause abnormal bleeding.

Quick summary

["HHT can increase your risk of bleeding problems, so early genetic testing may help guide prevention and treatment options."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
112327-2
Short code
HIPF multigene analysis Bld/T
Synonyms
HIPF multigene analysis Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
CPT
86038
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is Hereditary Hemorrhagic Telangiectasia (HHT)?

HHT is a genetic disorder where tiny, fragile blood vessels appear in the skin, mucous membranes, and organs. These vessels can leak blood easily, causing nosebleeds, easy bruising, or bleeding in the digestive tract. It’s usually inherited but can sometimes occur spontaneously.

How Does This Test Work?

Your blood sample is analyzed to detect specific genetic mutations (HHT1 or HHT2) that increase your risk of HHT. This helps confirm a diagnosis if symptoms are present or assess risk if you have family members with HHT.

Why Might You Need This Test?

You may be referred for this test if you have symptoms like frequent nosebleeds, easy bruising, or blood in stool, or if you have a family history of HHT. It can also help plan family counseling or prenatal testing if applicable.

What to Expect Before the Test

No special preparation is needed. A healthcare provider will take a small blood sample from your arm. The test is usually done in a lab and results may take several days to weeks.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test helps identify genetic mutations associated with HHT, which can influence treatment decisions, risk management, and family planning. Early detection may allow for proactive care, such as monitoring for bleeding risks or preventive measures.

Short name

HHT Gene Screening (blood)

Frequently asked questions

What symptoms might indicate HHT?
Symptoms can include frequent nosebleeds, easy bruising, blood in urine or stool, or recurrent mouth or gastrointestinal bleeding. If you have a family history of unexplained bleeding, this test may be recommended.
How long does it take to get results?
Results typically take 7–14 days, depending on lab processing. Your healthcare provider will discuss them with you once available.
Is this test covered by insurance?
Coverage depends on your insurance plan and clinical indication. Check with your provider or insurance company to confirm coverage before the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy