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Histidine concentration (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of histidine, an amino acid found in your blood, which plays a role in protein synthesis and cell growth.

Quick summary

["Histidine levels may help assess certain metabolic or nutritional conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13398-3
Short code
Histidine Amn-mCnc
Synonyms
Histidine Amn-mCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if they suspect conditions affecting amino acid metabolism, such as certain genetic disorders, liver disease, or kidney problems. It could also be part of a broader evaluation for malnutrition or metabolic imbalances.

What to Expect Before the Test

No special preparation is typically needed. You may be asked to fast for a few hours before the blood draw, but always follow your provider’s instructions. Avoid strenuous activity the day of the test.

How the Test Is Performed

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a slight prick, but it usually doesn’t cause discomfort. The blood will be sent to a lab for analysis.

What the Results Mean

Results are interpreted by your healthcare provider based on your overall health, medical history, and symptoms. Abnormal levels may indicate underlying issues that need further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Histidine Level

Frequently asked questions

How long does it take to get my results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will contact you once they have the results.
What does an abnormal histidine level mean?
An abnormal result doesn’t necessarily mean you have a specific condition. It may prompt further testing or evaluation by your provider to identify the underlying cause, such as genetic testing or additional bloodwork.
Can diet affect histidine levels?
Yes, diet can influence histidine levels. Foods high in protein, such as meat, fish, eggs, and dairy, contain histidine. If you suspect dietary factors are affecting your results, discuss this with your provider before interpreting the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy