Histidine concentration in serum or plasma

Why Might This Test Be Ordered?

Your healthcare provider may order this test to evaluate conditions affecting amino acid metabolism, such as histidinemia (a rare genetic disorder) or to monitor treatment for metabolic disorders. It may also be part of broader metabolic screening, especially in newborns or individuals with suspected inborn errors of metabolism.

What Does This Test Involve?

A blood sample is taken from a vein in your arm. The sample is then processed to measure the histidine concentration using a specialized laboratory technique. The result helps determine if your body is producing or processing histidine normally.

What Are Common Causes for Testing?

Tests for histidine levels are often conducted in cases of suspected histidinemia, genetic metabolic disorders, or when monitoring patients on specific diets or medications that may affect amino acid metabolism. It may also be part of routine newborn screening in some regions.

What Do the Results Mean?

Results may indicate whether your histidine levels are higher or lower than expected. Elevated levels could suggest certain metabolic conditions, while lower levels might indicate other underlying issues that require further evaluation by your healthcare provider.