Histiocyte Area in Urine (High-Performance Liquid Chromatography)
This test measures the presence and quantity of histiocytes, a type of white blood cell, in your urine. Histiocytes may appear in urine when there’s an immune response, inflammation, or certain medical conditions.
["This test helps assess immune system activity or kidney-related issues by detecting unusual cells in urine."]
Key facts at a glance
- LOINC
- 26027-3
- Short code
- Histiocytes #/area UrnS HPF
- Synonyms
- Histiocytes #/area UrnS HPF
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- microscopy-light-hpf
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like persistent fever, unexplained weight loss, or signs of infection. It could also be used to monitor conditions affecting the immune system, such as certain cancers or chronic inflammatory diseases.
What to Expect Before the Test
No special preparation is needed. You’ll likely provide a urine sample in a clean container, similar to a routine urine test. Avoid excessive exercise or strenuous activity before the test if instructed by your provider.
What the Results Mean
Elevated levels of histiocytes in urine may indicate an immune response, infection, or kidney involvement. However, normal results don’t rule out all conditions, so discuss your results with your provider for personalized interpretation.
Common Conditions Linked to Histiocyte Presence
High counts of histiocytes in urine can be associated with conditions like chronic infections, certain cancers (such as lymphoma), or autoimmune diseases. Your provider will consider your full medical history and symptoms when evaluating results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
While histiocytes are normally found in small amounts in urine, their presence in larger quantities can signal underlying health concerns. This test is often used as part of a broader diagnostic evaluation to identify immune system dysfunction or kidney pathology. Results should be interpreted alongside clinical findings and other diagnostic tests.
Short name
Urine Histiocyte Count
Frequently asked questions
What does a positive result mean?
Can diet or medications affect this test?
How often will I need this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy