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Histiocyte count in urine (microscopic examination)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of abnormal white blood cells called histiocytes in your urine, which may indicate an infection, inflammation, or other underlying conditions in your urinary tract or kidneys.

Quick summary

["Histiocytes in urine can signal possible infections or kidney issues that need further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38994-0
Short code
Histiocytes UrnS Ql Micro
Synonyms
Histiocytes UrnS Ql Micro
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like frequent urination, pain during urination, fever, or unexplained blood or pus in your urine. It’s also used to investigate conditions like kidney disease, urinary tract infections, or certain types of kidney stones.

What to Expect Before the Test

No special preparation is needed. You’ll likely provide a urine sample in a clean container, often during a routine office visit or lab visit. If you’re using medications that could affect urine color or clarity, let your provider know.

What the Test Involves

A healthcare professional will collect a urine sample, which is then examined under a microscope to count histiocytes (a type of immune cell) among other cells. This is a simple, non-invasive procedure.

What the Results Mean

Results are typically reported as a count of histiocytes per microliter of urine. Elevated counts may suggest inflammation, infection, or other conditions affecting your urinary system.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High levels of histiocytes in urine can indicate conditions such as urinary tract infections, interstitial nephritis (a type of kidney inflammation), or certain types of kidney disease. While histiocytes alone may not be diagnostic, they often prompt further testing to identify the root cause.

Short name

Urine Histiocyte Count

Frequently asked questions

What causes histiocytes to appear in urine?
Histiocytes in urine can result from infections (like urinary tract infections), kidney inflammation, or immune responses to certain kidney conditions. Stress, medications, or other systemic illnesses may also play a role.
How long does it take to get results?
Results are usually available within 1 to 3 business days, depending on lab processing times. Your provider will discuss them with you during your follow-up visit.
Can I take anything to prepare for this test?
No special preparation is needed, but avoid using strong medications that could alter urine color (like certain antibiotics) unless advised by your provider. Drink plenty of water to ensure a clear urine sample if possible.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy