Histology Examination of Tissue for Cancer Diagnosis (with Behavioral/Pathological Assessment)
A small sample of tissue is examined under a microscope to check for cancer cells or other abnormalities. This test helps doctors diagnose, stage, or monitor cancer.
["This test may be used to confirm suspected cancer or guide treatment decisions."]
Key facts at a glance
- LOINC
- 59847-4
- Short code
- Histology and Behavior ICD-O-3 Cancer
- Synonyms
- Histology and Behavior ICD-O-3 Cancer
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Critical range
- 0.5 N/A – —
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is Tissue Histology Used For?
Histology involves studying the microscopic structure of cells and tissues. In cancer testing, it helps identify abnormal cell growth patterns, such as tumors, by examining how cells look and behave under a microscope. This can confirm whether cancer is present and determine its type and spread.
How Is the Tissue Sample Collected?
A biopsy is typically performed using a needle or surgical removal of a small tissue sample. The sample is then sent to a lab where it is prepared for microscopic examination. Sometimes, additional tests like immunohistochemistry may be done to provide more detailed information about the cancer type.
Preparation and Examination Process
The tissue sample is fixed, sliced into thin sections, and stained to highlight different structures. A pathologist reviews these slides under a microscope to identify cancerous cells, their characteristics, and any signs of metastasis (spread to other areas).
When Might This Test Be Ordered?
This test is often recommended if you have symptoms like unexplained weight loss, persistent lumps, unexplained bleeding, or if cancer has been suspected based on imaging tests (e.g., MRI, CT scan). It may also be used during cancer treatment to monitor response or recurrence.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test is critical for cancer diagnosis, staging, and treatment planning. Histological findings help determine the grade (how aggressive the cancer is) and stage (how far it has spread), which guides treatment options such as surgery, chemotherapy, or radiation. Accurate results ensure the most effective and personalized care.
Short name
Tissue biopsy analysis for cancer
Frequently asked questions
Why might I need to fast before this test?
How long does it take to get results from this test?
Can this test be done at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy