Histological examination of cancer tissue (pathology evaluation)
This test involves examining a sample of tissue removed from your body to check for signs of cancer, such as abnormal cell growth or cancerous tumors. It helps doctors determine if cancer is present, its type, and how advanced it is.
["A tissue biopsy helps guide treatment decisions and monitor cancer progression."]
Key facts at a glance
- LOINC
- 42066-1
- Short code
- Histology ICD-O-1 Cancer
- Synonyms
- Histology ICD-O-1 Cancer
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Critical range
- 0.5 N/A – —
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why is this test done?
Doctors may recommend this test if you have symptoms like unexplained weight loss, persistent lumps, unusual bleeding, or if you have a family history of cancer. It’s also used before surgery, radiation, or chemotherapy to plan treatment. Sometimes, it’s done to confirm a diagnosis after other tests, like imaging scans, show suspicious areas.
How is the tissue sample collected?
A small piece of tissue is taken from the suspected cancer area using a needle (biopsy) or surgically removed. The sample is then sent to a lab where pathologists study it under a microscope to identify abnormal cells. Common methods include fine-needle aspiration, core needle biopsy, or surgical excision.
What happens during the lab process?
Once received, the tissue is fixed, sliced into thin sections, and stained with dyes to highlight different cell structures. Pathologists examine these slides to look for cancer cells, their patterns, and any signs of metastasis (spread to other parts of the body). Advanced techniques, like immunohistochemistry, may also be used to identify specific proteins associated with cancer types.
How long does it take to get results?
Results are typically available within 1 to 2 weeks, depending on the complexity of the sample and the lab’s workload. In some cases, especially if additional tests or consultations are needed, results may take longer.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical significance
Short name
Tissue biopsy analysis for cancer
Frequently asked questions
How can I prepare for this test?
What are the risks or side effects?
No, this test examines the tissue sample for cancer cells but may not detect all types of cancer, especially if the tumor is very small or in an early stage. Advanced imaging or genetic testing may be needed for certain cases.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy