Histological examination of cancer tissue (case-specific)
This test involves analyzing tissue samples from a cancer diagnosis to examine cellular structures and identify cancerous changes.
["Histology helps doctors understand cancer type and behavior by closely inspecting tissue under a microscope."]
Key facts at a glance
- LOINC
- 21996-4
- Short code
- Histology O/R Cancer case
- Synonyms
- Histology O/R Cancer case
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Critical range
- 0.5 N/A – —
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is Histological Examination Used For?
Histological examination, or histology, is performed to study the microscopic structure of tissues removed from a cancer case. It helps pathologists identify abnormal cells, determine the type of cancer, and assess how aggressive it may be. This detailed analysis supports treatment planning and guides decisions about surgery, radiation, or other therapies.
How Is Tissue Sampled for Histology?
Tissue samples are obtained during procedures like surgery, biopsy, or fine-needle aspiration. The sample is then fixed, sliced into thin sections, and stained to highlight cellular details for microscopic examination.
Role in Cancer Diagnosis and Staging
Histology plays a critical role in confirming cancer presence, classifying its subtype, and staging the disease. By examining features such as cell shape, growth patterns, and invasion into surrounding tissues, pathologists provide essential information for treatment strategies and prognosis.
How Does This Test Differ from Other Cancer Tests?
Unlike blood or imaging tests (e.g., biomarkers or scans), histology directly examines tissue under a microscope. It provides qualitative insights into cellular abnormalities that may not be detectable through other methods alone.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Why might I need this test?
How long does it take to get results from this test?
What if the histology report shows cancer but my symptoms were mild?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy