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HIV Antibody and Antigen Combination Test (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects both HIV antibodies and the virus itself (antigen) in your blood to help determine if you have been infected with HIV.

Quick summary

["A quick way to check for HIV infection, often used during initial screening or follow-up testing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32602-5
Short code
HIV1+2 Ab CSF Ql
Synonyms
HIV1+2 Ab CSF Ql
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86701
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What the Test Measures

The test looks for two key markers: HIV antibodies (produced by your immune system after infection) and HIV antigens (direct viral proteins). Antibodies typically appear within weeks to months after exposure, while antigens may appear sooner, sometimes within days.

How the Test Works

Your blood sample is analyzed using immunoassay techniques (likely immunofluorescent or chemiluminescent methods) to detect these markers. This method is highly sensitive and specific for identifying HIV infection.

Why It’s Important

Early detection of HIV is critical for managing the infection effectively. This test helps doctors confirm or rule out HIV infection quickly, allowing for timely treatment and support.

Sample Collection and Preparation

A small blood sample is drawn from your arm. The blood is processed to separate serum or plasma, which is then tested in a lab. This process is quick and typically done in a clinical setting.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HIV 1/2 Antibody/Antigen Screen

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 1 to 3 business days, depending on your healthcare provider’s lab processing times.
Can I have false positives or false negatives with this test?
While this test is highly accurate, rare cases of false positives or false negatives can occur. If your results are positive, further confirmatory testing may be recommended to ensure accuracy.
Do I need to prepare in any special way before this test?
No special preparation is needed. You can eat, drink, or take medications as usual on the day of the test. Avoiding alcohol or heavy meals right before the test may help ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy