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HIV Antibody Screening and Confirmation Test (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the human immunodeficiency virus (HIV), which your body produces in response to infection. It helps determine if you’ve been exposed to HIV.

Quick summary

["This test screens for HIV antibodies to identify potential infection early."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44873-8
Short code
HIV1+2 Ab Ser Ql IB
Synonyms
HIV1+2 Ab Ser Ql IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
86701
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

Your healthcare provider will take a blood sample from a vein in your arm. The blood is then processed to separate serum or plasma, which is tested for HIV antibodies using an immunoassay method. This test is designed to detect antibodies produced by your immune system in response to HIV infection, typically appearing within weeks to months after exposure.

Test Preparation

No special preparation is needed for this test. You may have a mild bruise or soreness at the injection site, but this usually goes away quickly. Avoid alcohol before the test if possible, as it may affect blood clotting.

What to Expect After the Test

After the blood draw, you can return to your normal activities immediately. If you experience any unusual bleeding or pain, contact your healthcare provider. Results will be reviewed by a medical professional and shared with you based on standard clinical protocols.

When Results Are Needed

HIV antibody tests are typically performed as part of routine screening, especially for high-risk groups or during specific health check-ups. Results may take several days to a few weeks to be processed and reported, depending on lab workflows.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate the presence of HIV antibodies, suggesting recent or past infection. While antibodies are a key marker, they do not confirm active HIV virus replication. Follow-up testing, such as viral load testing, may be recommended to assess disease progression and guide treatment decisions. Negative results mean no detectable antibodies at the time of testing, but HIV could still be present if exposed recently. Always consult your healthcare provider for interpretation of results in the context of your medical history and risk factors.

Short name

HIV Antibody Test

Frequently asked questions

How soon can I get results?
Results timing varies by lab. Some labs provide preliminary results within days, while final confirmatory results may take up to 2–4 weeks. Your provider will discuss timelines with you during the test process.
What if my test is positive?
A positive HIV antibody test requires confirmation with additional testing, such as a Western blot or nucleic acid test. Treatment options and support services will be tailored to your needs, including access to antiretroviral therapy and counseling to manage the infection.
Can I get false positives?
While rare, false positives can occur due to cross-reactions with other viruses or medications. If your test is positive, follow-up testing will confirm the result. Healthcare providers use multiple steps to minimize errors in HIV testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy