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HIV and Hepatitis C Virus Antibody Screening and Confirmatory Test Panel (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to HIV (human immunodeficiency virus) and hepatitis C virus (HCV), which your body makes in response to these infections. Antibodies are proteins that help identify and fight foreign substances, like viruses.

Quick summary

["This screening helps detect possible infections that may require further medical evaluation or treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
103565-8
Short code
HIV1,2+HCV+HEV RNA+HBV DNA S/P/B Dr Napb
Synonyms
HIV1,2+HCV+HEV RNA+HBV DNA S/P/B Dr Napb
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
86701
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects antibodies against HIV and HCV in your blood. Antibodies are part of your immune system’s response to these viruses. If your body has been exposed to either virus, your blood will likely contain these antibodies. This test does not directly measure the virus itself but helps determine if your immune system has recognized it.

How the Test Works

The test uses immunoassay methods (such as enzyme-linked immunosorbent assay, or ELISA) to identify antibodies. These methods detect specific proteins in your blood that match the virus’s structure. Results are interpreted by a healthcare provider to determine if antibodies are present.

Why It’s Important

Early detection of HIV or HCV is critical. These infections can be managed effectively with treatment, and early intervention can prevent serious health complications like organ damage or weakened immunity.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm or hand to draw blood. If you’re nervous, let your healthcare provider know—they can help make the process more comfortable.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HIV/HCV Antibody Panel

Frequently asked questions

Why might my healthcare provider order this test?
Your healthcare provider may recommend this test if you have risk factors for HIV or HCV, such as unprotected sex, sharing needles, or living with someone who has these infections. It may also be part of routine screening if you’re pregnant, have a weakened immune system, or have been exposed to these viruses.
What does a positive result mean?
A positive result means your blood contains antibodies to HIV or HCV, suggesting past or current infection. This does not confirm the exact type of virus or its severity. Follow-up tests may be needed to confirm the diagnosis and guide treatment.
What if my test results are negative?
A negative result means your blood did not contain detectable antibodies to these viruses at the time of testing. However, it’s important to continue practicing safe behaviors and discuss ongoing prevention with your healthcare provider, as infections can develop over time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy