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HIV Antibody Screening Test (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the human immunodeficiency virus (HIV), which your body makes in response to the virus. It helps determine if you’ve been exposed to HIV.

Quick summary

["This screening test is the first step in checking for HIV infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7917-8
Short code
HIV1 Ab Ser Ql
Synonyms
HIV1 Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86701
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for HIV antibodies in your blood or plasma. Antibodies are proteins your immune system produces after exposure to HIV. If your body has been exposed to HIV, these antibodies may be present. This test is designed to detect antibodies that appear within weeks to months after infection.

How the Test Works

Your healthcare provider will take a blood sample. The sample is tested using an immunoassay method to identify HIV antibodies. This method is highly sensitive and specific for detecting HIV antibodies in most cases.

Why It’s Done

HIV antibody screening is typically performed as part of routine health check-ups, especially for high-risk groups (e.g., sexually active individuals, people with multiple sexual partners, intravenous drug users, or those with sexually transmitted infections). It can also be recommended if you’ve had unprotected sex with someone whose HIV status is unknown or if you suspect exposure.

What to Expect Before the Test

There are usually no special preparations needed. You may be asked to fast before the test, but this is not always required. Bring any medications you’re currently taking, as some may affect test results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HIV Antibody Screen

Frequently asked questions

If your test is positive, further testing (like a confirmatory HIV antibody test or viral load test) will be needed to confirm HIV infection. A positive result means you may have HIV, and immediate medical evaluation is crucial for managing the infection and preventing complications.
A positive result indicates the presence of HIV antibodies, suggesting past or current infection. Follow-up testing and consultation with a healthcare provider are essential to determine next steps, including treatment options and counseling.
What does a negative result mean?
A negative result means no detectable HIV antibodies were found in your sample at the time of testing. However, HIV can sometimes take weeks to months to produce detectable antibodies. If you suspect exposure, retesting after 3 months is recommended for accurate results.
How soon can I get results?
Results are typically available within a few days to a week, depending on your healthcare provider’s lab processes. Follow-up instructions will guide you on next steps, including whether additional testing is needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy