HIV-1 Antibody Screening and Confirmation by Qualitative Immunoassay (Serum/Plasma)
This test detects antibodies to the human immunodeficiency virus (HIV), which your body makes in response to the virus. It helps determine if you have been exposed to HIV.
["HIV antibody testing is crucial for early detection and managing potential infection."]
Key facts at a glance
- LOINC
- 89374-3
- Short code
- HIV1 Ab Spec Ql IA
- Synonyms
- HIV1 Ab Spec Ql IA
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 86701
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
HIV antibody tests are often performed as part of routine health checkups, especially if you have risk factors for HIV, such as unprotected sex, shared needles, or exposure to infected blood. They may also be recommended if you have symptoms like unexplained weight loss, frequent infections, or fatigue. Some healthcare providers may screen all adults at higher risk during regular visits.
How the Test Works
The test uses a blood sample (either serum or plasma) to detect HIV antibodies through a qualitative immunoassay method. This means the test tells you whether antibodies are present but does not provide a precise amount. The result is either positive (indicating possible exposure) or negative (no detectable antibodies).
What the Results Mean
A positive result suggests you may have been infected with HIV, but further testing is needed to confirm. A negative result means no detectable antibodies were found at the time of testing. False negatives can occur if tested too soon after exposure, so follow-up testing may be advised.
Next Steps and Follow-Up
If your result is positive, your healthcare provider will likely order additional tests (like a viral load test) to confirm HIV infection and determine your treatment options. If negative, retesting after 3–6 months is recommended if you suspect recent exposure. Always discuss results with your provider to understand next steps.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
HIV Antibody Test (Screen & Confirm)
Frequently asked questions
What does a positive result mean?
How soon after exposure can I get a positive result?
Can I have a false positive result?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy