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HIV-1 Antibody Test (Qualitative) – Antibody to HIV-1 gp160

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to a specific protein (gp160) found in the HIV-1 virus, helping determine if your body has developed an immune response to HIV infection.

Quick summary

["A positive result suggests possible exposure to HIV, but further testing is needed for confirmation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35440-7
Short code
HIV1 gp160 Ab Sal Ql IB
Synonyms
HIV1 gp160 Ab Sal Ql IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
86701
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test identifies antibodies against the gp160 protein of HIV-1, a key structural protein in the virus. These antibodies are produced by your immune system in response to infection. The presence of these antibodies indicates exposure to HIV, though they may take weeks to months to develop after infection.

How the Test Works

This is a qualitative immunoassay (IA) test performed on serum or plasma. It detects antibodies bound to the HIV-1 gp160 protein using a labeled detection system, typically resulting in a visual or electronic signal indicating a positive or negative result.

Why It’s Ordered

Doctors may order this test as part of routine screening, during pregnancy, for sexually transmitted infection evaluation, or after potential exposure to HIV. It is often used as an initial screening step before confirmatory testing.

What to Expect Before the Test

No special preparation is needed. You may have a blood draw from a vein in your arm. If you’re pregnant or breastfeeding, inform your healthcare provider before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result means your immune system has detected HIV-1 gp160 antibodies, which may indicate past or recent infection. However, a negative result does not definitively rule out HIV. False negatives can occur if infection is very recent or if the test was taken too early. Always follow up with additional testing for confirmation.

Short name

HIV-1 gp160 Antibody Screen

Frequently asked questions

What does a positive result mean?
A positive result suggests your body has developed antibodies to HIV-1 gp160, which may mean you’ve been exposed to the virus. This does not confirm HIV infection alone—further testing is required to diagnose HIV.
Can I get this test at home?
No, this test is typically performed in a clinical laboratory using a blood sample drawn by a healthcare professional. Home testing kits for HIV antibodies exist but are different from this specific test.
How soon after exposure can I get a positive result?
Antibodies may take weeks to months to develop after exposure. A negative result early after exposure could be due to the window period before antibodies appear, so retesting may be recommended.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy