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HIV-1 Antibody Test (Qualitative) – HIV gp160 Protein

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the HIV-1 gp160 protein, a marker used to screen for past or current HIV infection. It helps determine if your immune system has responded to the virus, even if you’re not yet showing symptoms.

Quick summary

["This screening test may identify HIV exposure, prompting further evaluation if needed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9660-2
Short code
HIV1 gp160 Ab Ser Ql IB
Synonyms
HIV1 gp160 Ab Ser Ql IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
86701
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have risk factors for HIV (e.g., unprotected sex, shared needles, or exposure to infected blood), symptoms of infection, or if you’re part of a routine screening program. It’s also used during pregnancy or before certain medical procedures to check for infection.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein in your arm. You may feel a slight pinch, but it usually takes a few minutes to complete. If you’re pregnant or breastfeeding, let your provider know before testing.

What the Test Results Mean

A positive result means your body has detected antibodies to HIV-1 gp160, suggesting past or current infection. A negative result means no detectable antibodies were found at this time, but HIV could still be present without antibodies (e.g., in early infection). Follow-up testing (like a confirmatory HIV antibody test) is often needed for a definitive diagnosis.

What Happens Next

If your test is positive, your provider will likely order additional tests (e.g., HIV viral load or antibody confirmation) to confirm infection and guide treatment. If negative, they may recommend retesting later if you have ongoing risk factors.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HIV gp160 Antibody Screen

Frequently asked questions

What does a positive result mean?
A positive result means your blood contains antibodies to HIV-1 gp160, which could indicate past or current infection. This doesn’t confirm HIV alone—further testing is needed to diagnose the virus.
Can this test detect HIV if I’ve been exposed recently?
No, this test may not detect HIV immediately after exposure, especially in the first few weeks. Antibodies take time to develop, so follow-up testing may be recommended if you suspect recent risk.
Is this test different from an HIV viral load test?
Yes. This test checks for antibodies to a viral protein, while an HIV viral load test measures the actual amount of virus in your blood. Both are important for diagnosis and monitoring.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy