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HIV-1 Antibody Screening and Confirmation Test (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the human immunodeficiency virus (HIV), which your body produces in response to the virus. It helps determine if you have been exposed to HIV.

Quick summary

["This test screens for HIV infection, which can be critical for early treatment and management."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12870-2
Short code
HIV1 gp34 Ab Ser Ql IB
Synonyms
HIV1 gp34 Ab Ser Ql IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
86701
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may recommend this test if you have risk factors for HIV, such as unprotected sex, shared needles, or other behaviors that increase exposure. It’s also part of routine testing for certain groups, like people with sexually transmitted infections (STIs) or those with frequent medical check-ups.

How the Test Works

The test uses a blood sample (serum or plasma) to check for antibodies against HIV. If your body has been exposed to the virus, these antibodies will be present. The test is first screened (qualitative) and then confirmed to ensure accuracy.

Sample Collection and Preparation

A small blood sample is drawn from your arm, usually by a healthcare provider. The blood is processed to separate serum or plasma for testing. This process is quick and typically done in a lab.

What to Expect Before the Test

No special preparation is needed for this test. You may have a mild bruise or soreness at the injection site, but this usually goes away quickly. If you’re on blood-thinning medication, let your doctor know before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HIV Antibody Test

Frequently asked questions

If the test is positive, it means you have HIV antibodies, indicating past or current infection. Further testing may be needed to confirm the diagnosis and determine the virus’s stage. Early detection allows for timely treatment to manage symptoms and improve long-term health.
Results are typically available within 1–3 business days, depending on lab processing times. Your doctor will discuss the results with you, including any follow-up actions.
A positive result means your blood contains antibodies to HIV, suggesting you may have been infected at some point. This does not confirm active infection without additional testing, so your doctor will guide next steps, such as confirmatory tests or viral load checks.
Can I still have HIV if my antibody test is negative?
Yes, it’s possible. HIV antibodies may take weeks to develop after exposure. If you suspect exposure, ask your doctor about retesting after 3–6 months or using a different testing method, such as a viral load test.
How long does it take to get results?
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy