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HIV-1 p24 Antigen Antibody Test (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the p24 protein of the HIV virus in your blood. It helps screen for HIV infection by identifying your immune system’s response to the virus.

Quick summary

["This test helps determine if you’ve been exposed to HIV and may be part of routine screening or follow-up care."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35448-0
Short code
HIV1 p24 Ab Sal Ql IB
Synonyms
HIV1 p24 Ab Sal Ql IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
86701
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of HIV (like fever, fatigue, or swollen lymph nodes), have risk factors for HIV (like unprotected sex or shared needles), or are part of a routine screening program. It can also be used during pregnancy or for people with HIV-related conditions to monitor treatment response.

How the Test Works

The test uses a blood sample to detect antibodies against the p24 protein, a key part of the HIV virus. If your body has been exposed to HIV, your immune system produces antibodies to fight it. This test checks for those antibodies using a sensitive immunoassay method.

Sample Collection

A small amount of blood is drawn from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The blood is then sent to a lab for testing.

What to Expect After the Test

After the blood draw, you can usually return to your normal activities immediately. You may experience mild bruising or soreness at the injection site, but this typically goes away within a few days. Avoid strenuous activity for a short time to prevent excessive bleeding.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HIV p24 Antibody Screening

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 24 to 72 hours, depending on your healthcare provider’s lab processes. Your provider will contact you once results are ready.
Can I have my blood drawn if I’m pregnant?
Yes, this test is safe to perform during pregnancy. It’s often included in routine prenatal screenings to check for HIV exposure.
What if my test is positive?
A positive result means your body has detected HIV antibodies, which may indicate current or past infection. Your healthcare provider will guide you through next steps, which may include additional testing, counseling, and starting antiretroviral therapy if needed to manage the virus.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy