HIV p24 Antigen Quantitative, Serum/Plasma
This test measures the amount of p24 protein, a marker produced by the HIV virus, in your blood. It helps track HIV infection progression and response to treatment.
["This test helps monitor HIV levels and treatment effectiveness over time."]
Key facts at a glance
- LOINC
- 42339-2
- Short code
- HIV1 p24 Ag SerPl IA-mCnc
- Synonyms
- HIV1 p24 Ag SerPl IA-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 86701
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is the Purpose of This Test?
HIV p24 antigen testing is primarily used to detect HIV infection early and assess how the virus is responding to treatment. While not as sensitive as HIV antibody tests, it can provide additional information when used alongside other tests, especially in early or advanced stages of infection.
How Is the Test Performed?
A blood sample is drawn from a vein in your arm. The sample is then sent to a lab for analysis using a sensitive immunoassay method to detect the presence of p24 protein.
What Does a Positive Result Mean?
A positive result indicates the presence of HIV p24 antigen, meaning the virus is actively producing this protein. This can happen during early infection or in later stages if the virus is replicating. It does not replace antibody tests but complements them for comprehensive monitoring.
How Does This Test Differ from Other HIV Tests?
Unlike HIV antibody tests (e.g., ELISA or rapid tests), which detect antibodies your immune system produces against HIV, this test measures the virus itself by detecting p24 protein. It can sometimes detect HIV earlier than antibody tests but is less commonly used for initial diagnosis.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Monitoring HIV Progression and Treatment Response
Short name
HIV p24 Antigen
Frequently asked questions
Why might my doctor order this test?
What if my test results are abnormal?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy