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HIV-1 Subtype Detection by Nucleic Acid Amplification Probe (CSF)

Published: August 9, 2026Updated: August 16, 2026

This test checks for specific types (subtypes) of the HIV-1 virus in cerebrospinal fluid (CSF) using a nucleic acid amplification probe. It helps determine if the virus has spread to the central nervous system.

Quick summary

["Assists in diagnosing HIV-1 subtype presence in CSF for further treatment planning."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87962-7
Short code
HIV 1 subtype CSF NAA+probe
Synonyms
HIV 1 subtype CSF NAA+probe
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
86701
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms or test results suggesting HIV-1 infection in the brain or spinal cord, such as meningitis, seizures, or neurological issues. It’s also used in research or specialized care for HIV subtypes.

What to Expect Before the Test

No special preparation is needed. A healthcare professional will collect a small amount of CSF through a procedure called lumbar puncture (spinal tap). You may feel mild pressure or discomfort during the procedure.

How the Test Works

The CSF sample is tested for specific genetic sequences of HIV-1 subtypes using a probe-based nucleic acid amplification technique. This detects the virus’s genetic material to identify its subtype.

What the Results Mean

Positive results indicate the presence of a particular HIV-1 subtype in your CSF. This can guide treatment decisions, especially if the virus has affected the nervous system. Negative results mean no detectable subtype was found in this sample.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HIV-1 Subtype CSF NAAT Probe

Frequently asked questions

What does a positive result mean for my health?
A positive result suggests the presence of a specific HIV-1 subtype in your spinal fluid, which may indicate the virus has spread to the nervous system. This finding helps your healthcare team adjust your treatment plan to address the subtype more effectively.
Will this test affect my HIV treatment?
Not directly. This test provides subtype information to guide treatment decisions, but your overall HIV treatment will still be based on your viral load, CD4 count, and other clinical factors. Your provider will discuss how the results fit into your care plan.
How often will I need this test?
The frequency depends on your medical needs. Your healthcare provider may recommend it during specific stages of your HIV care, such as when symptoms suggest CNS involvement or as part of research protocols. Follow-up will be determined by your treatment team.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy