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HIV Antibody Test (Qualitative) – gp80 Protein

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the HIV gp80 protein, a marker used in screening for HIV infection. It helps identify if your immune system has responded to the virus.

Quick summary

["This screening helps determine if you may have been exposed to HIV."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11078-3
Short code
HIV2 gp80 Ab Ser Ql IB
Synonyms
HIV2 gp80 Ab Ser Ql IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
86701
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for antibodies produced by your immune system in response to the HIV gp80 protein. These antibodies indicate a past or current infection. This is a qualitative test, meaning it provides a yes/no result rather than a precise measurement.

How the Test Works

Blood is drawn and tested using an immunoassay method to detect the presence of antibodies against the gp80 protein. If antibodies are found, it suggests exposure to HIV, though further testing is needed for confirmation.

Why It’s Done

This test is typically part of routine HIV screening, especially for high-risk groups, or as part of pre-exposure prophylaxis (PrEP) evaluation. It helps monitor for infection before symptoms appear.

What to Expect Before the Test

No special preparation is needed. You may have a slight bruise or discomfort at the injection site, but most people find it quick and painless.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HIV Antibody Screen (gp80)

Frequently asked questions

If your test is positive, it does not confirm HIV infection alone. Follow-up testing (such as a confirmatory HIV antibody test) is required to diagnose HIV. A positive result means you should seek medical advice promptly for further evaluation.
A positive result means your body has detected antibodies to the HIV gp80 protein, which may indicate past or current infection. This is not a definitive diagnosis and should be followed up with additional testing.
What does a positive result mean?
A positive result means your blood contains antibodies to the HIV gp80 protein. This suggests you may have been exposed to HIV, but it does not confirm the infection. You should discuss next steps with your healthcare provider.
Can I get false positives?
While rare, false positives can occur, especially in early infection or with certain medical conditions. Your healthcare provider will guide you on follow-up testing to clarify results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy