HIV Antibody Confirmation Test (Serum/Plasma)
This test checks for HIV antibodies in your blood to confirm an infection after an initial screening test. It helps confirm whether you have been exposed to the virus.
["This test confirms HIV infection by detecting antibodies your body makes in response to the virus."]
Key facts at a glance
- LOINC
- 45250-8
- Short code
- HIV confirmation facility Add
- Synonyms
- HIV confirmation facility Add
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- reported
- CPT
- 86701
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
The initial HIV screening test (often a rapid test or blood draw) may detect HIV antibodies or the virus itself. A confirmation test ensures accuracy by using a more sensitive method to confirm the presence of these markers. This step is crucial for proper diagnosis and treatment planning.
How the Test Works
Your blood sample is tested using an immunoassay method, which detects HIV antibodies (such as IgG) that your immune system produces after infection. The test looks for specific antibodies linked to HIV, not the virus itself.
Sample Collection and Preparation
A blood sample is drawn from a vein in your arm. The blood is processed to separate serum or plasma, which is then tested for HIV antibodies. This sample is sent to a laboratory for analysis.
Test Results and Interpretation
Results are reported as either positive (indicating HIV infection) or negative (no detectable antibodies). A positive result means you should follow up with a healthcare provider for further evaluation and treatment options.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
HIV confirmation is essential because it ensures accurate diagnosis. A positive result confirms HIV infection and guides healthcare providers in starting appropriate treatment, such as antiretroviral therapy (ART), which can help manage the virus and improve health outcomes. Early confirmation allows for timely medical support, monitoring, and support services.
Short name
HIV Confirmation
Frequently asked questions
What does a positive result mean?
How soon after exposure can I get tested?
Can I have false positives or false negatives?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy