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HIV Genotype Test (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test identifies the specific type (genotype) of the HIV virus in your blood. Knowing your genotype helps healthcare providers tailor treatment options to your needs.

Quick summary

["Understanding your HIV genotype helps guide personalized treatment plans."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48558-1
Short code
HIV Gentyp Islt
Synonyms
HIV Gentyp Islt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
genotyping
CPT
86701
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The HIV genotype test detects the genetic sequence variations of the HIV virus. These variations can affect how the virus responds to antiretroviral medications. The test uses a blood sample to analyze the virus’s genetic material, typically through a specialized laboratory technique that identifies precise genetic markers.

How the Test Works

Your healthcare provider will take a blood sample from a vein in your arm. The sample is then sent to a lab where genetic sequencing is performed to determine the HIV genotype. This process involves extracting viral RNA or DNA from your blood and analyzing it for specific mutations that define the virus’s subtype.

Why It Matters in Treatment

Genotype testing is crucial because different HIV subtypes may require different medications. For example, some subtypes may be more resistant to certain drugs, and knowing your genotype helps ensure your treatment is effective and avoids resistance.

When You Might Need This Test

You may need an HIV genotype test if your HIV levels (viral load) are low but your symptoms persist, if you’ve been on antiretroviral therapy (ART) for a while, or if your doctor suspects drug resistance. It’s also used when starting new medications to confirm the best options for your specific virus type.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HIV Genotype

Frequently asked questions

When should I get this test?
This test is typically recommended if you’re on HIV medication and need to check for resistance, if your viral load is low but you’re still experiencing symptoms, or if your doctor suspects changes in your virus’s behavior. It’s not a routine test for everyone but is important for those on long-term treatment.
What does the test result mean?
The result will show the specific subtype (genotype) of the HIV virus in your blood. This information helps your healthcare provider choose the most effective medications to treat you. If resistance to certain drugs is detected, alternative treatments may be recommended to avoid ineffective or harmful side effects.
How long does it take to get results?
HIV genotype test results usually take about 1 to 2 weeks to process and return. Your healthcare provider will contact you once the results are ready, so plan to follow up with them during this time.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy