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Genetic Test for Human Immunodeficiency Virus (HIV) Resistance/Susceptibility via Serological Plasma Sample

Published: August 9, 2026Updated: August 16, 2026

This test analyzes your blood to check how certain HIV medications might affect you. It helps doctors choose the best treatment plan for your specific genetic makeup.

Quick summary

["Helps tailor HIV treatment to reduce side effects and improve effectiveness based on your genetic profile."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49659-6
Short code
HIV RT Susc Pnl Islt Genotyp
Synonyms
HIV RT Susc Pnl Islt Genotyp
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
genotyping
CPT
86701
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may recommend this test if you have HIV and are starting new treatment, experiencing side effects, or if your virus has developed resistance to previous medications. It’s also used in research or specialized care plans.

What to Expect Before the Test

You’ll have a simple blood draw, usually taken from your arm. No special preparation is needed, but tell your doctor about any medications you’re taking.

How the Test Works

Your blood sample is tested to identify specific genetic variations (mutations) in genes related to HIV resistance. This helps determine how your body may respond to antiviral drugs.

What the Results Mean

Results show which genes carry variations that could affect drug effectiveness. This information helps your healthcare team adjust your treatment to avoid resistance or reduce side effects.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is primarily used to guide personalized HIV treatment plans. By identifying genetic markers, doctors can select medications that are more likely to work well for you, improving treatment success and reducing the risk of drug resistance over time.

Short name

HIV Resistance/Susceptibility Genotyping

Frequently asked questions

Will I need to fast before this test?
No fasting is required. However, inform your doctor about any medications you’re taking, as they may affect test results or your treatment plan.
How long will it take to get my results?
Results are typically available within 1–2 weeks, depending on lab processing and follow-up testing. Your doctor will discuss the findings with you during your appointment.
Can this test be done on other body fluids besides blood?
This specific test is performed on plasma (a component of blood). If you have questions about alternative testing methods, ask your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy